Process Up-Scaling
日期:2022-12-09 阅读量:1314
Our team has more than years of experience in R&D and production, providing scale-up production validation for various microbial or enzyme catalysis products and APIs, with exclusive contract plants in 1-60 ton size level fermentation tanks and the associated recovery and purification equipment.
l Experiential scaling-up method: It is mainly based on experience to figure out the characteristics of bioreactor through step-by-step scale-up. It is also the main method currently used in drug synthesis.
l Similarity scaling-up method: the main purpose is to apply the similarity principle for scaling-up. This method has some limitations which is only applicable to the scaling-up of physical process. It is not applicable to the scaling-up of chemical process.
l Simulation scaling-up: It is the scaling-up of application of computer technology and it is the direction of future development